Detailed material

BioMed Central Journal?British Journal

Publication Date: April, 2010

Title of Article：

Inhibition of metastasis, angiogenesis, and tumor growth with Chinese herbal cocktail Tien-Hsien Liquid.

Research author：

Dr.Sun Andy, Dr. Chia Jean-San, Dr. Wang Won-Bo, Dr. Chiang Chun Pin

Research unit：

Graduate Institute of Microbiology, National Taiwan University, College of Medicine
Dental Dept., National Taiwan University

Research unit Conclusions：

Chinese herbal cocktails designed to maximize the synergistic and minimize the antagonistic interactions among various phytochemicals present in different herbs may have therapeutic efficacy against multifactorial diseases such as cancer. In this study, we demonstrated that the Chinese herbal cocktail THL could inhibit cancer metastasis and angiogenesis by targeting multiple biological and pathological processes in cancer cells. We also demonstrated that THL, which was delivered one week after tumor implantation, could exert anti-tumor effects but had no adverse effect on body weight in immune-compromised mice, implicating that THL has potential to be used as a therapeutic agent for established tumors. Moreover, our preliminary results also indicated that oral delivery of THL could inhibit tumor growth and induce anti-tumor immunity in immune-competent mice (J-L Du and W-B Wang, data not shown). Together these data suggest that THL is a promising cancer therapeutic agent and merits further investigation.

Journal Introduction：

The BioMed Central was established in 2001. It is an electronic medical journal available to access through its website. It mainly collects research papers on cancer research that includes pathology, biology, prevention, diagnosis, and therapy. It also contains articles on the latest trends of cell biology, genetics, epidemiology, and clinical medicine. Impact Factor for 2011 is 3.01.

Link to Journal：

website address：http://www.biomedcentral.com

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